Autonomic dysfunction in chronic inflammatory demyelinating polyradiculoneuropathy

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Autonomic dysfunction in chronic inflammatory demyelinating polyradiculoneuropathy.

OBJECTIVES Autonomic deficits in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have not been adequately quantitated. The Composite Autonomic Severity Score (CASS) is a validated instrument for laboratory quantitation of autonomic failure derived from standard autonomic reflex tests. We characterized dysautonomia in CIDP using CASS. METHODS Autonomic function was retrospecti...

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Chronic inflammatory demyelinating polyradiculoneuropathy.

The syndrome of acute inflammatory idiopathic polyneuropathy is well known, the predominently motor type of which is recognised by the name of Guillain-Barre Syndrome (GBS), in which the maximum neurological deficit develops rapidly in days, plateaus for weeks and then subsides with the recovery occurring in weeks to months. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) has e...

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Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Related Disorders

The first case of recurrent neuritis was published by Eichhorst in 1890 (1). In 1958, Austin (2) described steroid responsiveness, recurrence and cerebrospinal fluid (CSF) protein elevation. Dyck and colleagues (3) described the clinicopathological findings of monophasic progression, steady deterioration, stepwise progression and recurrence, with histologic peripheral nervious system (PNS) infl...

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Pathogenesis of chronic inflammatory demyelinating polyradiculoneuropathy.

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a term applied to a spectrum of immune-mediated demyelinating neuropathies that are heterogeneous in clinical manifestations and probably in pathogenesis. Although histopathologic studies of CIDP have been complicated by a relapsing course of the inflammatory reaction and its predominance in proximal nerve segments, many clues point to...

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Chronic Inflammatory Demyelinating Polyneuropathy Chronic Inflammatory Demyelinating Polyradiculoneuropathy – An Overview of Intravenous Immunoglobulin Therapy

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a significant source of disability, and early diagnosis and immunomodulatory therapy administration are critical to minimise disease progression and axonal degeneration. Intravenous immunoglobulin (IVIg) therapy is considered to be a first-line treatment for CIDP. Comparative shortand long-term data of IVIg versus corticosteroi...

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ژورنال

عنوان ژورنال: Neurology

سال: 2012

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0b013e3182494d66